Human Adiponectin, ADP ELISA Kit

Full product name

Adiponectin

Code

E1550Hu

Assay type

Sandwich

Size

48T,96T

Sensitivity

0.11mg/L

Detection range

0.2-60mg/L

Sample type

Serum, plasma, cell culture supernates

Species

Human

Storage

2-8ºC

Assay time

1h 30m

Background

Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.

UniProt accession

Q15848

MASS?Da?

26,414

GeneID

9370

Synonyms

30 kDa adipocyte complement-related protein;ACRP30;Adipocyte complement-related 30 kDa protein;Adipocyte, C1q and collagen domain-containing protein;Adiponectin;Adipose most abundant gene transcript 1 protein;APM 1;APM1;apM-1;Gelatin-binding protein

Gene names

APM1

Research area

Others

Target protein

APM1