Human Asprosin, ASPROSIN ELISA Kit
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Full product name
Asprosin
Code
E4095Hu
Assay type
Sandwich
Size
48T,96T
Sensitivity
0.23ng/ml
Detection range
0.5-100ng/ml
Sample type
Serum, Plasma, Urine, Ascites, Cerebrospinal fluid, Tissue
Species
Human
Storage
2-8°C
Assay time
1h 30m
Background
Asprosin is a hormone that targets the liver to increase plasma glucose levels. Asprosin is secreted by white adipose tissue and circulates in the plasma. Asprosin acts in response to fasting and promotes blood glucose elevation by binding to the surface of hepatocytes. It promotes hepatocyte glucose release by activating the protein kinase A activity in the liver, resulting in rapid glucose release into the circulation. Asprosin and Fibrillin-1 are encoded by single FBN1 gene, they are translated and secreted as single precursor protein. Upon secretion these two proteins are separated by furin.
Research area
Signal Transduction
Target protein
ASPROSIN
https://pubmed.ncbi.nlm.nih.gov/35844162/
https://pubmed.ncbi.nlm.nih.gov/32608281/
https://pubmed.ncbi.nlm.nih.gov/36281766/