Human Calprotectin, CAL ELISA Kit

Full product name

calprotectin

Code

E4010Hu

Assay type

Sandwich

Size

48T,96T

Sensitivity

1.67ng/ml

Detection range

2-600ng/ml

Sample type

Serum, Plasma, Urine, Ascites, Cerebrospinal fluid, Tissue

Species

Human

Storage

2-8°C

Assay time

1h 30m

Background

Calprotectin(S100A9) is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis, adhesion, can increase the bactericidal activity of neutrophils by promoting phagocytosis via activation of SYK, PI3K/AKT, and ERK1/2 and can induce degranulation of neutrophils by a MAPK-dependent mechanism . Predominantly found as calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions.

Research area

Immunology|Signal Transduction|Cell Biology|Epigenetics and Nuclear Signaling|Cancer

Target protein

CAL

https://pubmed.ncbi.nlm.nih.gov/35096423/