Human Interleukin 1?, IL-1B ELISA Kit

Full product name

Interleukin 1 beta

Code

E0143Hu

Assay type

Sandwich

Size

96T,48T

Sensitivity

10.07pg/mL

Detection range

20-6000pg/mL

Sample type

Serum, plasma, cell culture supernates

Species

Human

Storage

2-8ºC

Assay time

1h 30m

Background

Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells (PubMed: 10653850). Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6 (PubMed: 12794819).

UniProt accession

P01584

MASS?Da?

30,748

GeneID

3553

Synonyms

Catabolin;IL 1B;IL 1beta;IL-1 beta;IL1B;Interleukin-1 beta

Gene names

IL1B

Research area

Immunology; Microbiology; Cardiovascular; Metabolism

Target protein

IL1B