Human Interleukin 1?, IL-1B ELISA Kit
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Full product name
Interleukin 1 beta
Code
E0143Hu
Assay type
Sandwich
Size
96T,48T
Sensitivity
10.07pg/mL
Detection range
20-6000pg/mL
Sample type
Serum, plasma, cell culture supernates
Species
Human
Storage
2-8ºC
Assay time
1h 30m
Background
Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells (PubMed: 10653850). Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6 (PubMed: 12794819).
UniProt accession
P01584
MASS?Da?
30,748
GeneID
3553
Synonyms
Catabolin;IL 1B;IL 1beta;IL-1 beta;IL1B;Interleukin-1 beta
Gene names
IL1B
Research area
Immunology; Microbiology; Cardiovascular; Metabolism
Target protein
IL1B