Human Interleukin 18, IL-18 ELISA Kit

Full product name

Interleukin 18

Code

E0147Hu

Assay type

Sandwich

Size

96T,48T

Sensitivity

0.2ng/L

Detection range

0.5-100ng/L

Sample type

Serum, plasma, cell culture supernates

Species

Human

Storage

2-8ºC

Assay time

1h 30m

Background

A proinflammatory cytokine primarily involved in polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses (Probable). Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators (PubMed: 14528293, PubMed: 25500532). Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells (Probable) (PubMed: 10653850).

UniProt accession

Q14116

MASS?Da?

22,326

GeneID

3606

Synonyms

Iboctadekin;IFN-gamma-inducing factor;IL 18;IL-1 gamma;IL18;IL-18;Interferon gamma-inducing factor;Interleukin-1 gamma;Interleukin-18;

Gene names

IL18

Research area

Immunology

Target protein

IL18

https://pubmed.ncbi.nlm.nih.gov/35705877/