Human Interleukin 4, IL-4 ELISA Kit

Full product name

Interleukin 4

Code

E0092Hu

Assay type

Sandwich

Size

96T,48T

Sensitivity

2.53ng/L

Detection range

5-1000ng/L

Sample type

Serum, plasma, cell culture supernates

Species

Human

Storage

2-8ºC

Assay time

1h 30m

Background

Participates in at least several B-cell activation processes as well as of other cell types (PubMed: 3016727). It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages (By similarity). Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4 (By similarity).

UniProt accession

P05112

MASS?Da?

17,492

GeneID

3565

Synonyms

B-cell stimulatory factor 1;Binetrakin;BSF-1;IL 4;IL4;IL-4;Interleukin-4;Lymphocyte stimulatory factor 1;Pitrakinra;

Gene names

IL4

Research area

Immunology; Cancer

Target protein

IL4

https://pubmed.ncbi.nlm.nih.gov/24460857/

https://pubmed.ncbi.nlm.nih.gov/28578295/