Rat Interleukin 1 Beta, IL-1B ELISA Kit

Full product name

Rat Interleukin 1beta

Code

E0119Ra

Assay type

Sandwich

Size

48T,96T

Sensitivity

0.08ng/ml

Detection range

0.2-60ng/ml

Sample type

Serum, plasma, cell culture supernates

Species

Rat

Storage

2-8ºC

Assay time

1h 30m

Background

IL-1? is a member of the interleukin 1 family of cytokines. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.

UniProt accession

Q63264

MASS?Da?

30644

GeneID

373606

Synonyms

IFN beta inducing factor;IL 1;IL 1 beta;IL1;IL-1;IL1 BETA;IL-1 beta;IL1B;IL-1B;il1b-A;IL1F2;Interleukin 1 beta;Interleukin 1 beta precursor;interleukin 1, beta;Interleukin-1 beta;OAF;Osteoclast activating factor;OTTHUMP00000162031

Gene names

IL1B

Research area

Immunology

Target protein

IL1B